Playing as UCLA, I struggled and lost against Hawaii, was blown out against Indiana, and was surprisingly competitive (given the past two results) but lost against LSU. I hadn't expected Indiana to be the hardest one of the bunch but so far that has been true.
For those looking forward, I actually beat Oregon, got blown out at Penn State, and then went on a winning streak against Minnesota, Rutgers, Nebraska, and Iowa before losing to UW and USC (haven't played Fresno State yet)
Of course, most of this is simply because I suck at playing the game, but I'm still surprised at how well the game predicted how difficult each opponent would be.
Did I mention that my defense frequently left receivers uncovered, the rush had a hard time getting to the QB without blitzing, the O-line was unable to create room for my RB to run, and my receivers never got open (the last one might be on me though)?